A major difference I noticed was clarity of mind. It was an immediate reaction, like a lifting of that foggy sensation that invades the mind. I am 57 years old and have a stressful career. Since taking NeuroSpark my stress levels are more manageable, I feel calmer, find it easier to stay focused, my attention span has increased and memory has improved. I have taken quite a few different brands of fish oil and none have had as dramatic results as NeuroSpark.